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22140

Sigma-Aldrich

Celite® 545

filter aid, treated with sodium carbonate, flux calcined

Synonym(s):

Diatomaceous earth, flux-calcined

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$79.80
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$270.00

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1 KG
$79.80
5 KG
$270.00

About This Item

CAS Number:
68855-54-9
EC Number:
272-489-0
MDL number:
MFCD00132803
UNSPSC Code:
11101527
PubChem Substance ID:
329752266
NACRES:
SB.54

$79.80

In StockDetails

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Quality Level

200

form

powder

quality

flux calcined
treated with sodium carbonate

composition

Al2O3, 1.0%
CaO, 6.73%
Fe2O3, 0.46%
Na2O + K2O, 1.88%
SiO2, 89.0%

median particle size

≤125.30 μm (71% (acc. to Cilas))

pH

>8.5 (25 °C, 10% in aq. suspension)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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General description

Diatomaceous earth is made up of natural amorphous silica formed from the fossilized skeletons of diatoms.[1] It is extracted, crushed, dried and calcined with flux material. DE is widely used as filler in construction materials, paints and as an anti-caking agent for agricultural chemicals.[2] It has high water and oil absorption ability.[1]

Application

Diatomaceous earth may be used as an adsorbent for column chromatography.[3]

Caution

Not Intended for cGMP Parenteral Pharmaceutical Manufacturing

Legal Information

Celite is a registered trademark of Imerys Minerals California, Inc.

pictograms

Health hazard
GHS08

signalword

Danger

hcodes

H372

Hazard Classifications

STOT RE 1 Inhalation

target_organs

Lungs

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL5160
BCCL5159
BCCJ6336
BCCK0476
BCCK0475

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Direct immobilization of polyphenol oxidases on Celite 545 from ammonium sulphate fractionated proteins of potato (Solanum tuberosum).
Khan AA, et al.
Journal of Molecular Catalysis. B, Enzymatic, 40(1), 58-63 (2006)
Immobilization of lipases on clay, Celite 545, diethylaminoethyl-, and carboxymethyl-Sephadex and their interesterification activity.
Ansari SA and Husain Q.
Biotechnol. Tech., 12(5), 381-384 (1998)
Lactose hydrolysis from milk/whey in batch and continuous processes by concanavalin A-Celite 545 immobilized Aspergillus oryzae ? galactosidase.
Ansari SA and Husain Q.
Food and Bioproducts Processing, 90(2), 351-359 (2012)
Violeta Chitu et al.
Cell reports, 30(9), 3004-3019 (2020-03-05)
CSF-1R haploinsufficiency causes adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP). Previous studies in the Csf1r+/- mouse model of ALSP hypothesized a central role of elevated cerebral Csf2 expression. Here, we show that monoallelic deletion of Csf2 rescues most behavioral deficits
Yueru Li et al.
The American journal of pathology, 190(9), 1971-1981 (2020-06-27)
Leakage of retinal blood vessels, which is an essential element of diabetic retinopathy, is driven by chronic elevation of vascular endothelial growth factor (VEGF). VEGF quickly relaxes the endothelial cell barrier by triggering signaling events that post-translationally modify pre-existing components
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Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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