W450001

Choline chloride

FCC

• Synonym(s): (2-Hydroxyethyl)trimethylammonium chloride
• Linear Formula: (CH₃)₃N(Cl)CH₂CH₂OH
• CAS Number: 67-48-1
• Molecular Weight: 139.62
• FEMA Number: 4500
• Beilstein/REAXYS Number: 3563126
• EC Number: 200-655-4
• MDL number: MFCD00011721
• UNSPSC Code: 12164502
• PubChem Substance ID: 329830721
• NACRES: NA.21

Properties

• biological source: synthetic
• Quality Level: 400
• grade: Halal; Kosher
• reg. compliance: FCC; FDA 21 CFR 117
• form: powder, crystals or chunks
• color: white
• mp: 302-305 °C (dec.) (lit.)
• application(s): flavors and fragrances
• documentation: see Safety & Documentation for available documents
• food allergen: no known allergens
• organoleptic: fishy
• SMILES string: [Cl-].C[N+](C)(C)CCO
• InChI: 1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
• InChI key: SGMZJAMFUVOLNK-UHFFFAOYSA-M

Description

General description

Choline chloride (ChCl) is a quaternary ammonium salt. The unusual solvent properties of eutectic mixtures of urea and choline chloride make it useful as a biodegradable ambient-temperature solvent for a number of applications.

Application

• Profiling and optimized extraction of bioactive polyphenolic compounds from young, red-fleshed apple using eco-friendly deep eutectic solvents.: This research demonstrates the use of choline chloride-based deep eutectic solvents (DES) as a green alternative for extracting polyphenolic compounds from apples. The study highlights DESs effectiveness in yielding high-quality extracts, which could revolutionize natural product extraction processes in the food industry (Yu et al., 2024).


• 17beta-estradiol induces hyperresponsiveness in guinea pig airway smooth muscle by inhibiting the plasma membrane Ca(2+)-ATPase.: This research utilizes choline chloride in physiological experiments to investigate the mechanisms through which estradiol affects calcium signaling in airway smooth muscle. The findings could lead to better understanding and treatment of asthma and other respiratory disorders (Romero-Martinez et al., 2024).


• DES-ultrasonication treatment of cellulose nanocrystals and the reinforcement in carrageenan biocomposite.: In this study, choline chloride is used to create a novel biocomposite material, demonstrating its potential in enhancing the mechanical properties of biodegradable plastics. This could lead to new advancements in sustainable material science (Ramli et al., 2024).


• A sensitive determination of Brilliant Blue FCF in some food samples using hydrophillic deep eutectic solvent-assisted magnetic nano gel-based dispersive solid phase microextraction prior to spectrophotometric analysis.: This innovative approach uses choline chloride in a deep eutectic solvent formulation to improve the detection of food dyes. The method promises greater efficiency and sensitivity, crucial for food safety and compliance (Erek et al., 2024).

Substrates

Choline acetyltransferase substrate

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable