Journal of agricultural and food chemistry, 60(21), 5471-5481 (2012-05-09)
This study examined the environmental and genetic variation in methyl donor contents and compositions of 200 cereal genotypes. Glycine betaine, choline, and trigonelline contents were determined by (1)H NMR, and significant differences were observed between cereal types (G) and across
Coffee shows distinct antimicrobial activity against several bacterial genera. The present study investigated molecular mechanisms and active ingredients mediating the antimicrobial effect of coffee. Depending on concentration, roasted, but not raw coffee brew inhibited the growth of Escherichia coli and
International immunopharmacology, 14(4), 740-748 (2012-10-30)
Oxidative stress and apoptotic cell death in kidney have been suggested as contributing factors in the development and complication of diabetes especially in diabetic nephropathy (DN). This study investigated the effects of trigonelline (TG) on the renal functional, morphological changes
Journal of agricultural and food chemistry, 58(13), 7489-7496 (2010-06-17)
A capillary electrophoresis method with UV detection was developed for the first time for the determination of the pyridine betaine trigonelline (N-methylnicotinic acid) in seeds and vegetable oils. Analytical characteristics of the method showed its good performance in terms of
Current medicinal chemistry, 19(21), 3523-3531 (2012-06-12)
There is evidence that Trigonella foenum-graecum L. (fenugreek), a traditional Chinese herb, and its components are beneficial in the prevention and treatment of diabetes and central nervous system disease. The pharmacological activities of trigonelline, a major alkaloid component of fenugreek
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.