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S0817

Sigma-Aldrich

Sodium chloride solution

0.85%

Synonym(s):

Halite, NaCl, sodium chloride

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About This Item

Linear Formula:
NaCl
CAS Number:
Molecular Weight:
58.44
Beilstein/REAXYS Number:
3534976
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

Quality Level

concentration

0.83-0.86% NaCl
0.85%

density

1.000 g/cm3 at 20 °C

SMILES string

[Na+].[Cl-]

InChI

1S/ClH.Na/h1H;/q;+1/p-1

InChI key

FAPWRFPIFSIZLT-UHFFFAOYSA-M

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General description

Sodium chloride is commonly referred to as “salt” and is naturally present as mineral halite. Sodium chloride solution is highly used in chemical production.

Application

Sodium chloride solution has been used in the preparation of neurotoxin 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine (MPTP) stock solution.

Biochem/physiol Actions

Sodium chloride solution is applicable in protein crystallization. It favours better protein-protein interactions.

Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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A model of MPTP-induced Parkinson's disease in the goldfish
Weinreb O and Youdim MB
Nature Protocols, 2(11) (2007)
Sodium Chloride
Kirk-Othmer Encyclopedia of Chemical Technology, 1-27 (2000)
Hydrophobic forces between protein molecules in aqueous solutions of concentrated electrolyte.
Curtis RA, et al.
Biophysical Chemistry, 98(3), 249-265 (2002)
Guus M Bol et al.
EMBO molecular medicine, 7(5), 648-669 (2015-03-31)
Lung cancer is the most common malignancy worldwide and is a focus for developing targeted therapies due to its refractory nature to current treatment. We identified a RNA helicase, DDX3, which is overexpressed in many cancer types including lung cancer
Matthew Gallon et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(35), E3604-E3613 (2014-08-20)
The sorting nexin 27 (SNX27)-retromer complex is a major regulator of endosome-to-plasma membrane recycling of transmembrane cargos that contain a PSD95, Dlg1, zo-1 (PDZ)-binding motif. Here we describe the core interaction in SNX27-retromer assembly and its functional relevance for cargo

Protocols

To standardize a procedure for the determination of protein by modified Lowry.

To standardize a procedure for the enzymatic assay of Deoxyribonuclease I.

Objective: To standardize a procedure for the enzymatic assay of Aprotinin.

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