PHR1122

Phenylethyl Alcohol

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(s): 2-Phenylethanol, β-PEA, 2-Phenylethyl alcohol, Benzyl carbinol, PEA
• Linear Formula: C₆H₅CH₂CH₂OH
• CAS Number: 60-12-8
• Molecular Weight: 122.16
• Beilstein/REAXYS Number: 1905732
• EC Number: 200-456-2
• MDL number: MFCD00002886
• UNSPSC Code: 41116107
• PubChem Substance ID: 329823143
• NACRES: NA.24

Properties

• grade: certified reference material; pharmaceutical secondary standard
• Quality Level: 300
• agency: traceable to USP 1533250
• vapor density: 4.21 (vs air)
• vapor pressure: 1 mmHg ( 58 °C)
• API family: phenylethyl alcohol
• CofA: current certificate can be downloaded
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• refractive index: n20/D 1.5317 (lit.)
• bp: 219-221 °C/750 mmHg (lit.)
• mp: −27 °C (lit.)
• density: 1.020 g/mL at 20 °C (lit.)
• application(s): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-30°C
• SMILES string: OCCc1ccccc1
• InChI: 1S/C8H10O/c9-7-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2
• InChI key: WRMNZCZEMHIOCP-UHFFFAOYSA-N

Description

General description

Phenylethyl alcohol, is a primary aromatic alcohol of high boiling point, having a characteristic rose-like odor. It presents organoleptic properties and impacts the quality of the wine, distilled beverages, and fermented foods. It shows its presence in fresh beer and is responsible for the rose-like odor of well-ripened cheese. It is commercially and industrially an important flavor and is a component of a variety of foodstuffs such as ice cream, gelatin, candy, pudding, chewing gum, and non-alcoholic beverages. It is formed by yeasts during fermentation of alcohols either by decomposition of L-phenylalanine or metabolism of sugar substrates.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Phenylethyl alcohol may be used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations by spectrophotometric and chromatographic techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3266 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H319
• pcodes: P264 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: 215.6 °F - closed cup
• flash_point_c: 102 °C - closed cup