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P8574

Sigma-Aldrich

Sodium pyruvate

BioXtra, ≥99%

Synonym(s):

α-Ketopropionic acid sodium salt, 2-Oxopropanoic acid sodium salt, Pyruvic acid sodium salt

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About This Item

Linear Formula:
CH3COCOONa
CAS Number:
Molecular Weight:
110.04
Beilstein/REAXYS Number:
3568341
EC Number:
MDL number:
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.71

product line

BioXtra

Quality Level

assay

≥99%

form

powder

impurities

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

mp

>300 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

2-8°C

SMILES string

[Na+].CC(=O)C([O-])=O

InChI

1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1

InChI key

DAEPDZWVDSPTHF-UHFFFAOYSA-M

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Application

Sodium pyruvate has been used as a component:
  • of cutting solution for rat brain tissue slice preparation
  • of M-199 medium for the maturation of oocytes
  • of Krebs-Henseleit buffer for plasma incubation

Biochem/physiol Actions

Sodium pyruvate based therapeutic regimen is effective for treating mitochondrial diseases. It decreases tissue damage associated with the pathophysiology of brain damage, haemorrhagic shock and ischemia-reperfusion injury models.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1B

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Imaging calcium concentration dynamics in small neuronal compartments
Yasuda R, et al.
Science's STKE : Signal Transduction Knowledge Environment, 2004(219) (2004)
Biomarkers and clinical rating scales for sodium pyruvate therapy in patients with mitochondrial disease
Koga Y, et al.
Mitochondrion (2019)
Transcriptome and proteome analysis of soleus muscle of hormone-sensitive lipase-null mice
Hansson O, et al.
Journal of Lipid Research, 46(12), 2614-2623 (2005)
Embryonic development after follicle culture is influenced by follicle-stimulating hormone isoelectric point range
Vitt UA, et al.
Biology of Reproduction, 65(5) (2001)
Addition of sodium pyruvate to stored red blood cells attenuates liver injury in a murine transfusion model
Xia S, et al.
Mediators of Inflammation, 2016 (2016)

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