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H2766

Sigma-Aldrich

Sodium 1-heptanesulfonate

Synonym(s):

1-Heptanesulfonic acid sodium salt

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5 G
$52.90
25 G
$215.00
100 G
$556.00

About This Item

Linear Formula:
C7H15O3SNa
CAS Number:
22767-50-6
Molecular Weight:
202.25
EC Number:
245-210-5
MDL number:
MFCD00007543
UNSPSC Code:
12161900
PubChem Substance ID:
24895533
NACRES:
NA.21

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biological source

synthetic (oragnic)

Quality Level

100

description

anionic

form

powder

mol wt

202.25 g/mol

technique(s)

HPLC: suitable
LC/MS: suitable

impurities

<2.0% water (Karl Fischer)

mp

300  °C (572 °F)

solubility

H2O: ≥100 mg/mL

cation traces

Na: 10.8-12.0 % (w/v) (anhydrous)

SMILES string

[Na+].CCCCCCCS([O-])(=O)=O

InChI

1S/C7H16O3S.Na/c1-2-3-4-5-6-7-11(8,9)10;/h2-7H2,1H3,(H,8,9,10);/q;+1/p-1

InChI key

REFMEZARFCPESH-UHFFFAOYSA-M

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General description

Sodium 1-heptanesulfonate belongs to the sodium alkylsulfonate group of surfactants. It has a -SO?3 head group with sodium and an alkyl chain attached to the head group. Sodium 1-heptanesulfonate has a critical micelle concentration value of 0.302 mol/dm3.[1]
Sodium 1-heptanesulfonate, also known as sodium heptanesulfonate, is a versatile compound commonly used in lab experiments and biochemical research. It acts as an ion-pairing agent, surfactant, and buffer, playing a crucial role in various applications. In biochemistry, it helps with tasks like protein purification and nucleic acid separation by reducing surface tension for better mixing. It also serves as a chelating agent for metal ion analysis and acts as a buffer in biological experiments. Sodium 1-heptanesulfonate is a preferred choice in HPLC and high-performance capillary electrophoresis analyses, aiding in the separation of positively charged analytes in both organic and inorganic compounds, from pharmaceuticals to peptide research.

Application

Sodium 1-heptanesulfonate has been used as a component of the mobile phase buffer for preequilibration of high performance liquid chromatography column.[2][3]
Ion-pairing reagent for HPLC, including analyses of peptides and proteins.

Biochem/physiol Actions

Sodium 1-heptanesulfonate serves as an ion-pairing reagent for analysis of epinephrine and norepinephrine in ion-pairing chromatography (IPC).[4]

Features and Benefits

  • Ideal for Cell Biology and Biochemical Research
  • High purity chemical suitable for multiple research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.

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Certificates of Analysis (COA)

Lot/Batch Number
0000413273
0000413272
0000413273
0000413272
0000373354

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Validated HPLC-Fl method for the analysis of S-adenosylmethionine and S-adenosylhomocysteine biomarkers in human blood
Albu C, et al.
Journal of Fluorescence, 23(3), 381-386 (2013)
Determination of S-adenosylmethionine and S-adenosylhomocysteine from human blood samples by HPLC-FL
Birsan C, et al.
Analytical Letters, 41(10), 1720-1731 (2008)
Analysis of catecholamines in urine by unique LC/MS suitable ion-pairing chromatography
Bergmann ML, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1057(2), 118-123 (2017)
A R Calhoun et al.
Journal of colloid and interface science, 309(2), 505-510 (2007-03-03)
Measurements have been made to determine the solubility of ethane, C2H6, in aqueous solutions of four different surfactants of the linear alkanesulfonate class at 25 degrees C. The surfactants, sodium 1-pentanesulfonate, sodium 1-hexanesulfonate, sodium 1-heptanesulfonate, and sodium 1-octanesulfonate, all share
Takeshi Oshizaka et al.
International journal of pharmaceutics, 475(1-2), 292-297 (2014-08-27)
Skin concentrations of topically administered compounds need to be considered in order to evaluate their efficacies and toxicities. This study investigated the relationship between the skin permeation and concentrations of compounds, and also predicted the skin concentrations of these compounds
View All Related Papers

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is the storage temperature for ALD00532?

    1 answer

    1. The product ALD00532 should be stored at room temperature.

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