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ED2P

Sigma-Aldrich

Ethylenediaminetetraacetic acid dipotassium salt dihydrate

≥98%

Synonym(s):

(Ethylenedinitrilo)tetraacetic acid dipotassium salt, Dipotassium ethylenediaminetetraacetate dihydrate, EDTA dipotassium salt, Edathamil, Potassium ethylenediaminetetraacetate dibasic

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100 G
$79.30
500 G
$270.90
1 KG
$445.00

About This Item

Linear Formula:
HOOCCH2(KOOCCH2)NCH2CH2N(CH2COOK)CH2COOH · 2H2O
CAS Number:
Molecular Weight:
404.45
EC Number:
UNSPSC Code:
12352107
NACRES:
NA.77

$79.30


Available to ship onApril 11, 2025Details


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biological source

synthetic

Quality Level

assay

≥98%

form

powder

reaction suitability

reagent type: chelator

pH

4.0-5.0 (25 °C, 40.4 g/L)

mp

255-280 °C (dec.) (lit.)

solubility

3 M KOH: 160 mg/mL, clear to very slightly hazy, colorless to faintly yellow

Storage temp.

room temp

SMILES string

O.O.O.O.[K+].[K+].[K+].[K+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2K.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

Inchi Key

JFROQFOCFOKDKU-UHFFFAOYSA-L

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Application

Ethylenediaminetetraacetic acid dipotassium salt dehydrate has been used as a component:
  • of EDTA–glycerol solution (EDTA-G) for decalcification[1]
  • of buffer for monoamine and pterine analysis[2]
  • of T-cell resuspension buffer[3]

Used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals

Biochem/physiol Actions

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood.[4] EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia.[5] EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis.[6] Calcium disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.[7] It also enhances the antimicrobial functionality of lysozyme and improves shelf life of cheese.[8]

Pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Inhalation

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves


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A novel decalcification method for adult rodent bone for histological analysis of peripheral-central nervous system connections
Begum F, et al.
Journal of Neuroscience Methods, 187(1), 59-66 (2010)
Cytochrome c oxidase activity is a metabolic checkpoint that regulates cell fate decisions during T cell activation and differentiation
Tarasenko TN, et al.
Cell Metabolism, 25(6), 1254-1268 (2017)
Whole body insulin responsiveness is higher in beef steers selected for increased muscling
McGilchrist P, et al.
Animal : An International Journal of Animal Bioscience, 5(10), 1579-1586 (2011)
Lysozyme/EDTA disodium salt and modified-atmosphere packaging to prolong the shelf life of burrata cheese
Conte A, et al.
Journal of Dairy Science, 94(11), 5289-5297 (2011)
Does calcium disodium EDTA slow CKD progression?
Weaver VM, et al.
American Journal of Kidney Diseases, 60(4), 503-506 (2012)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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