791725

Citric acid

anhydrous, free-flowing, Redi-Dri^™, ACS reagent, ≥99.5%

• Synonym(s): 2-Hydroxy-propane-1,2,3-tricarboxylic acid
• Linear Formula: HOC(COOH)(CH₂COOH)₂
• CAS Number: 77-92-9
• Molecular Weight: 192.12
• Beilstein/REAXYS Number: 782061
• EC Number: 201-069-1
• MDL number: MFCD00011669
• UNSPSC Code: 12352100
• PubChem Substance ID: 329768287
• NACRES: NA.21

Properties

• grade: ACS reagent; anhydrous
• Quality Level: 200
• product line: Redi-Dri^™
• assay: ≥99.5%
• form: crystals
• quality: free-flowing
• expl. lim.: 8 %, 65 °F
• impurities: Substances carbonizable by hot sulfuric acid, passes test
• ign. residue: ≤0.02%
• pKa: (1) 3.13, (2) 4.76, (3) 6.4
• mp: 153-159 °C (lit.)
• anion traces: chloride (Cl^-): ≤0.001%; oxalate (C₂O₄^2-): passes test (limit about 0.003%); phosphate (PO₄^3-): ≤0.001%; sulfate (SO₄^2-): ≤0.002%
• cation traces: Fe: ≤3 ppm; Pb: ≤2 ppm
• SMILES string: OC(=O)CC(O)(CC(O)=O)C(O)=O
• InChI: 1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
• InChI key: KRKNYBCHXYNGOX-UHFFFAOYSA-N

Description

General description

Citric acid also called 2-hydroxy-propane-1,2,3-tricarboxylic acid, is a component of the tricarboxylic acid cycle in all organisms. Industrial production of citric acid use fungal, yeast and citrus fruit as the major source. Aspergillus niger is majorly used for citric acid production by fermentation Manganese inhibits fermentative production of citric acid Oral supplementation of citric acid promotes tricarboxylic acid cycle and oxidative phosphorylation in mitochondria, attenuating physical fatigue.

Application

Citric acidhas been used as a component of citrate buffer and Fe-free sauton′s medium. It has been used in hybridization chain reaction buffer for preequilibration of coverslips for testes sections.

Legal Information

Redi-Dri^™ is a trademark of Sigma-Aldrich Co. LLC

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319,H335
• pcodes: P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable