46232

Dipyron monohydrate

VETRANAL^®, analytical standard

• Synonym(s): Metamizol, Methapyrone
• Empirical Formula (Hill Notation): C₁₃H₁₆N₃NaO₄S · H₂O
• CAS Number: 5907-38-0
• Molecular Weight: 351.35
• Beilstein/REAXYS Number: 3865381
• MDL number: MFCD00150293
• UNSPSC Code: 41116107
• PubChem Substance ID: 329757107
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 200
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): clinical; forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: O.[Na+].CN(CS([O-])(=O)=O)C1=C(C)N(C)N(C1=O)c2ccccc2
• InChI: 1S/C13H17N3O4S.Na.H2O/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;;/h4-8H,9H2,1-3H3,(H,18,19,20);;1H2/q;+1;/p-1
• InChI key: UNZIDPIPYUMVPA-UHFFFAOYSA-M
• Gene Information: human ... PTGS1(5742) , PTGS2(5743)

Description

General description

Metamizol is an active pharmaceutical ingredient with both analgesic and antipyretic effects, primarily used to relieve pain caused by neuritis and neuralgia.

Application

Metamizol may be used as a reference standard for the determination of metamizol in pharmaceutical formulations by reversed-phase high-performance liquid chromatography (RP-HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS08
• signalword: Warning
• hcodes: H361fd
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges