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About This Item
Linear Formula:
(CH3)2C=NOH
CAS Number:
Molecular Weight:
73.09
Beilstein/REAXYS Number:
1560146
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.02
Recommended Products
grade
purum
Quality Level
assay
≥98.0% (GC)
bp
135 °C (lit.)
mp
59-61 °C
60-63 °C (lit.)
density
0.901 g/mL at 25 °C (lit.)
functional group
amine
oxime
SMILES string
C\C(C)=N/O
InChI
1S/C3H7NO/c1-3(2)4-5/h5H,1-2H3
InChI key
PXAJQJMDEXJWFB-UHFFFAOYSA-N
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Related Categories
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Carc. 2 - Eye Dam. 1 - Flam. Sol. 2 - Skin Sens. 1B
Storage Class
4.1B - Flammable solid hazardous materials
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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M Rysková et al.
Folia biologica, 43(1), 19-24 (1997-01-01)
The genotoxic effects of N-nitroso-N-methylurea (MNU) and acetone oxime (ACOX) were tested in the Somatic Mutation and Recombination Test (SMART) in Drosophila melanogaster. We have performed the same assay on transgenic flies expressing the human gene encoding a glutathione S-transferase
C Kohl et al.
Carcinogenesis, 13(7), 1091-1094 (1992-07-01)
The hepatocarcinogenicity of acetoxime has been tentatively linked with its metabolic oxidation to the potent genotoxicant and carcinogen propane 2-nitronate (P2-N). In order to test the hypothesis that acetoxime is metabolized to P2-N, the oxime (20 mM) was incubated with
Stefanie Zorbas-Seifried et al.
Molecular pharmacology, 71(1), 357-365 (2006-10-20)
The presence of cis-configured exchangeable ligands has long been considered a prerequisite for antitumor activity of platinum complexes, but over the past few years, several examples violating this structure-activity relationship have been recognized. We report here on studies with the
N Guo et al.
Carcinogenesis, 11(9), 1659-1662 (1990-09-01)
The hepatocarcinogens 2-nitropropane and acetoxime have previously been found to induce a specific and qualitatively identical pattern of base damage in rat liver DNA and RNA, including the induction of increased levels of 8-hydroxyguanine. Because both 2-nitropropane and acetoxime are
J Torreilles et al.
Biochimie, 65(4-5), 295-298 (1983-04-01)
Preparation of adducts from nicotinamide adenine dinucleotide and a number of oximes is described; these include acetoxime, pyruvatoxime, cyclohexanoxime, cyclopentanoxime. These adducts are closely related to the corresponding NAD-ketone adducts in their spectra properties, but they are stable in acid
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