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870128P

Avanti

16:0 DBCO PE

Avanti Research™ - A Croda Brand 870128P, powder

Synonym(s):

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl

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About This Item

Empirical Formula (Hill Notation):
C56H90N3O10P
CAS Number:
2260670-42-4
Molecular Weight:
996.30
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 25 mg (870128P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870128P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCCNC(CCC(N1CC(C=CC=C2)=C2C#CC3=C1C=CC=C3)=O)=O)=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+]

General description

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl (16:0 DBCO PE) is a head group modified lipid containing dibenzocyclooctyne (DBCO). It is a widely used reagent in click chemistry.

Application

1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl (16:0 DBCO PE or DPPE-DBCO) has been used in preparation of DBCO-presenting lipid bilayers. It has also been used in preparation of clickable cubosomes for antibody-free drug targeting and imaging applications.

Packaging

5 mL Amber Glass Screw Cap Vial (870128P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

flash_point_f

No data available

flash_point_c

No data available

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simon Finn Mayer et al.
Biochimica et biophysica acta. Biomembranes, 1861(10), 183023-183023 (2019-07-22)
Pore-forming antimicrobial peptides (AMPs) are attracting interest as cytolytic antibiotics and drug delivery agents with potential use for targeting cancer cells or multidrug-resistant pathogens. Ceratotoxin A (CtxA) is an insect-derived cytolytic AMP with 36 amino acids that is thought to
Nicolas Alcaraz et al.
Bioconjugate chemistry, 29(1), 149-157 (2017-11-29)
The combination of copper-free click chemistry with metabolic labeling offers new opportunities in drug delivery. The objective of this study was to determine whether cubosomes functionalized with azide or dibenzocyclooctyne (DBCO) groups are able to undergo copper-free click chemistry with

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