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860669P

Avanti

Sphingosine (d16:1)

Avanti Research™ - A Croda Brand 860669P, powder

Synonym(s):

D-erythro-Sphingosine (C16 base)

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About This Item

Empirical Formula (Hill Notation):
C16H33NO2
Molecular Weight:
271.44
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (860669P-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860669P

lipid type

sphingolipids

shipped in

dry ice

Storage temp.

−20°C

SMILES string

OC[C@]([H])(N)[C@]([H])(O)/C=C/CCCCCCCCCCC

General description

Sphingosine (d16:1), also known as hexadecasphingosine or hexadecasphing-4-enine, is a minor sphingoid base with 16 carbon atoms.[1] It is one of the major sphingoid bases found in Musca domestica larvae and adults.[2]

Biochem/physiol Actions

Sphingosine is implicated in negative regulation of cell proliferation and stimulation of apoptosis.[3] It has a potential to control the activities of phospholipases, protein kinases, ion channels, cannabinoid receptor type 1 (CB-1) receptors and steroidogenic factor 1 (SF-1) receptors.[4]

Packaging

5 mL Amber Glass Screw Cap Vial (860669P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

No data available

flash_point_c

No data available

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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the
Lipid Mediators and Their Metabolism in the Brain (2011)
Ceramides and cerebrosides
Metabolism in the Nervous System, 179-199 (1983)
The occurrence of tetradecasphing-4-enine and hexadecasphing-4-enine as the principal sphingosines of Musca domestica larvae and adults.
L L Bieber et al.
Biochimica et biophysica acta, 187(1), 157-159 (1969-07-29)
Olivier Cuvillier
Biochimica et biophysica acta, 1585(2-3), 153-162 (2003-01-18)
The sphingolipid metabolites ceramide, sphingosine, and sphingosine 1-phosphate contribute to controlling cell proliferation and apoptosis. Ceramide and its catabolite sphingosine act as negative regulators of cell proliferation and promote apoptosis. Conversely, sphingosine 1-phosphate, formed by phosphorylation of sphingosine by a

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