857120P

14:0 Lyso PA

1-myristoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder

• Synonym(s): 1-tetradecanoyl-sn-glycero-3-phosphate (sodium salt); PA(14:0/0:0); 14:0 LPA; 110677
• Empirical Formula (Hill Notation): C₁₇H₃₄O₇PNa
• CAS Number: 325465-45-0
• Molecular Weight: 404.41
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• assay: >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
• form: powder
• packaging: pkg of 1 × 25 mg (857120P-25mg); pkg of 1 × 500 mg (857120P-500mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 857120P
• lipid type: phospholipids; cardiolipins
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCCCCCCC)=O.[Na+]

Description

General description

Lysophosphatidic acid (LPA) belongs to a class of phospholipids, that has a glycerol backbone attached by a phosphate group, an aliphatic chain and a hydroxyl group. It has a phosphate group attached to sn-3 position, an aliphatic chain attached to sn-1 or sn-2 position and the hydroxyl group attached to the remaining sn-1 or sn-2 position.

Application

14:0 Lyso PA is suitable to use as internal standard to spike serum samples for the extraction of serum lipids. It is also suitable to use as standard lipids for extraction of lipids and for quality control in multiple reaction monitoring (MRM) assay.

Biochem/physiol Actions

Lysophosphatidic acid (LPA) participates in several biological functions. It acts as a potential biomarker for detecting ovarian cancer. LPA stimulates platelet aggregation, smooth muscle contraction, chemotaxis, cytoskeleton rearrangement, Ca²⁺ mobilization, neurotransmitter release and cell proliferation.

Packaging

20 mL Clear Glass Screw Cap Vial (857120P-500mg)

5 mL Amber Glass Screw Cap Vial (857120P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class: 11 - Combustible Solids