700144P
Avanti
15:0 cholesteryl-d7 ester
Avanti Research™ - A Croda Brand 700144P, powder
Synonym(s):
cholesteryl-d7 pentadecanoate
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About This Item
Empirical Formula (Hill Notation):
C42H67D7O2
CAS Number:
Molecular Weight:
618.08
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (700144P-10mg)
pkg of 1 × 25 mg (700144P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 700144P
shipped in
dry ice
storage temp.
−20°C
General description
15:0 cholesteryl-d7 ester (cholesteryl-d7 pentadecanoate) is a deuterated form of cholesteryl pentadecanoate ester. Cholesterol is found in free and ester form in circulation. It associates with lipoproteins including very-low, low and high-density lipoproteins (VLDL, LDL and HDL). The synthesis of cholesteryl esters is mediated by acylCoA-cholesteryl-acyl transferase (ACAT) majorly in the endoplasmic reticulum of liver and intestinal cells.
Biochem/physiol Actions
A ratio of cholesteryl ester to cholesterol is lower in cardiovascular disorder. The esterified cholesterol serves as the storage version of cholesterol and its association with lipoproteins further adds a structural feature to them.
Packaging
5 mL Amber Glass Screw Cap Vial (700144P-10mg)
5 mL Amber Glass Screw Cap Vial (700144P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
Certificates of Analysis (COA)
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Mathias J Gerl et al.
Scientific reports, 8(1), 14764-14764 (2018-10-05)
Shotgun lipidomic analysis of 203 lipids in 13 lipid classes performed on blood plasma of donors who had just suffered an acute coronary syndrome (ACS, n = 74), or an ischemic stroke (IS, n = 21), or who suffer from stable angina pectoris (SAP
Babak Bagheri et al.
Medical archives (Sarajevo, Bosnia and Herzegovina), 72(2), 103-107 (2018-05-08)
The hypothesis is proposed that the atherogenicity of lipoporotein fractions is correlated with the content of unesterified cholesterol. To evaluate the role and prognostic values of unesterified and esterified cholesterol in lipoprotein fractions for coronary artery disease (CAD). The study
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