764248
Amino-PEG4-alkyne
Synonym(s):
3,6,9,12-Tetraoxapentadec-14-yn-1-amine, Acetylene-PEG4-amine, H2N-PEG4-propyne, Triethylene glycol 2-aminoethyl propargyl ether
Sign Into View Organizational & Contract Pricing
Select a Size
10 MG
$71.20
25 MG
$162.00
All Photos(1)
Select a Size
Change View
10 MG
$71.20
25 MG
$162.00
About This Item
Empirical Formula (Hill Notation):
C11H21NO4
CAS Number:
Molecular Weight:
231.29
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
form
liquid
Quality Level
reaction suitability
reaction type: click chemistry
reagent type: cross-linking reagent
functional group
alkyne
amine
storage temp.
−20°C
SMILES string
NCCOCCOCCOCCOCC#C
InChI
1S/C11H21NO4/c1-2-4-13-6-8-15-10-11-16-9-7-14-5-3-12/h1H,3-12H2
InChI key
QDLPAHLHHBCWOW-UHFFFAOYSA-N
Related Categories
Application
Heterobifunctional linker enabling the connection of an azide containing compound or biomolecule to one with a carboxylic acid. The amine group can be linked to a carboxylic acid through standard coupling procedures (EDC, product #39391, etc...) and the terminal alkyne will react with azides via copper-catalyzed 1,3-dipolar cycloaddition click chemistry. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification of carboxylic acid containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character.
Amino-PEG4-alkyne may be used to synthesize alkynyl-functionalized iron oxide nanoparticles (IONPs) for preparing glycopolymer-based iron oxide nanoparticles (GIONs) for potential bioscience applications.[1]
Storage Class
10 - Combustible liquids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Facile fabrication of glycopolymer-based iron oxide nanoparticles and their applications in the carbohydrate?lectin interaction and targeted cell imaging.
Shao C, et al.
Polym. Chem., 7(6), 1337-1344 (2016)
Strain-promoted azide?alkyne cycloaddition for protein?protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier
Singh S, et al.
Organic & Biomolecular Chemistry (2016)
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
