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Key Documents

545953

Sigma-Aldrich

1-Aminohydantoin hydrochloride

98%

Synonym(s):

1-Amino-2,4-imidazolidinedione hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C3H5N3O2 · HCl
CAS Number:
Molecular Weight:
151.55
Beilstein/REAXYS Number:
3699376
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

98%

mp

201-205 °C (lit.)

SMILES string

Cl[H].NN1CC(=O)NC1=O

InChI

1S/C3H5N3O2.ClH/c4-6-1-2(7)5-3(6)8;/h1,4H2,(H,5,7,8);1H

InChI key

WEOHANUVLKERQI-UHFFFAOYSA-N

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Application

1-Aminohydantoin hydrochloride may be used as one of the reactants in the synthesis of (E)-1-(2-hydroxybenzylideneamino)imidazolidine-2,4-dione, dantrolene and dantrolene sodium.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Yuli Xie et al.
Bioorganic & medicinal chemistry letters, 18(9), 2840-2844 (2008-04-25)
We report here a class of thiazolidine-2,4-diones and 2-thioxothiazolidin-4-ones as potent inhibitors of the lymphoid specific tyrosine phosphatase (Lyp) identified from high throughput screens. Chemical modification by incorporating the known phosphotyrosine (pTyr) mimics led to the discovery of a salicylate-based
Takamitsu Hosoya et al.
Bioorganic & medicinal chemistry, 17(6), 2490-2496 (2009-02-24)
Suzuki-Miyaura coupling of 3-azido-5-(azidomethyl)phenylboronic acid pinacol ester with various aryl bromides affords corresponding diazido-functionalized biaryl compounds in good yields. This approach provides an easy access to radioisotope-free photoaffinity probes possessing biaryl structure. By using this method, we prepared a novel
Abdelselam Ali et al.
Bioorganic & medicinal chemistry letters, 20(2), 649-652 (2009-12-08)
A series of hydrazonotrifluorosulfonanilide derivatives were synthesized and evaluated for in vitro activity against the ectoparasites Ctenocephalides felis and Rhipicephalus sanguineus. Some compounds with excellent activity against tick were identified.
Ascorbic Acid as an Initiator for the Direct C H Arylation of (Hetero) arenes with Anilines Nitrosated In Situ
Crisostomo, Fernando Pinacho, Tomas Martin, and Romen Carrillo
Angewandte Chemie (International Edition in English), 53.8 , 2181-2185 (2014)
William Andrew Publishing et al.
Pharmaceutical Manufacturing Encyclopedia, 1-4, 1193-1193 (2013)

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