Skip to Content
MilliporeSigma
All Photos(1)

Documents

47639

Sigma-Aldrich

Fmoc-His(Trt)-OH

≥98.0% (sum of enantiomers, HPLC), for peptide synthesis

Synonym(s):

Nα-Fmoc-N(im)-trityl-L-histidine

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C40H33N3O4
CAS Number:
Molecular Weight:
619.71
Beilstein/REAXYS Number:
5204720
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product name

Fmoc-His(Trt)-OH, ≥98.0% (sum of enantiomers, HPLC)

assay

≥98.0% (sum of enantiomers, HPLC)

optical activity

[α]/D 87±5°, c = 1 in chloroform

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

OC(=O)[C@H](Cc1cn(cn1)C(c2ccccc2)(c3ccccc3)c4ccccc4)NC(=O)OCC5c6ccccc6-c7ccccc57

InChI

1S/C40H33N3O4/c44-38(45)37(42-39(46)47-26-36-34-22-12-10-20-32(34)33-21-11-13-23-35(33)36)24-31-25-43(27-41-31)40(28-14-4-1-5-15-28,29-16-6-2-7-17-29)30-18-8-3-9-19-30/h1-23,25,27,36-37H,24,26H2,(H,42,46)(H,44,45)/t37-/m0/s1

InChI key

XXMYDXUIZKNHDT-QNGWXLTQSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Fmoc-His(Trt)-OH can be used as a building block in solid-phase peptide synthesis (SPPS).

Analysis Note

may contain ~1 equivalent solvent

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Design and evaluation of new pH-sensitive amphiphilic cationic lipids for siRNA delivery
Malamas AS, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 171(3), 296-307 (2013)
Yoonhee Bae et al.
International journal of pharmaceutics, 515(1-2), 186-200 (2016-11-05)
Glioblastoma multiform (GBM) is the most frequent and aggressive form of brain tumors in adults. However, the development of more efficient and safe nonviral vector gene therapy represents a promising therapeutic approach, using a tumor-specific killer gene, named apoptin. In
Tsukasa Mizutaru et al.
ACS applied materials & interfaces, 9(11), 9996-10002 (2017-03-11)
For exerting potential catalytic and photocatalytic activities of metal nanoparticles (MNPs), immobilization of MNPs on a support medium in highly dispersed state is desired. In this Research Article, we demonstrated that surfactant-free platinum nanoparticles (PtNPs) were efficiently immobilized on graphene
Yoonhee Bae et al.
Journal of pharmaceutical sciences, 106(6), 1618-1633 (2017-02-12)
Malignant glioma is the most common and aggressive form of primary brain tumor in adults. In this study, we describe the efficacy of nonviral gene delivery carriers, histidine- and arginine- or histidine- and lysine-grafted polyamidoamine (PAMAM) dendrimers (PAMAM-H-R and PAMAM-H-K)
Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences.
Coin I, et al.
Nature Protocols, 2(12), 3247-3247 (2007)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service