Skip to Content
MilliporeSigma
All Photos(2)

Documents

419869

Sigma-Aldrich

Ethynyl p-tolyl sulfone

98%

Synonym(s):

p-Toluenesulfonylacetylene, Tosylacetylene

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
CH3C6H4SO2C≡CH
CAS Number:
13894-21-8
Molecular Weight:
180.22
Beilstein/REAXYS Number:
2556169
MDL number:
MFCD00191647
UNSPSC Code:
12352100
PubChem Substance ID:
24866282
NACRES:
NA.22

assay

98%

mp

73-74 °C (lit.)

solubility

organic solvents: soluble(lit.)

SMILES string

Cc1ccc(cc1)S(=O)(=O)C#C

InChI

1S/C9H8O2S/c1-3-12(10,11)9-6-4-8(2)5-7-9/h1,4-7H,2H3

InChI key

FTHKWIMQNXVEHW-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Ethynyl p-tolyl sulfone (Tosylacetylene) may be used in the synthesis of 2-(4-methylphenylsulfonyl)ethenyl (tosvinyl, Tsv) protected derivatives. It may be used as starting reagent for the synthesis of optically active indan-2-ols.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Takeshi Hanazawa et al.
The Journal of organic chemistry, 68(12), 4980-4983 (2003-06-07)
An efficient and practical synthesis of optically active indan-2-ols 1 has been developed starting from readily accessible optically active 4-siloxy-1,6-alkadiynes 2 and ethynyl p-tolyl sulfone, where the metalative Reppe reaction mediated by an economical divalent titanium reagent, Ti(O-i-Pr)(4)/2 i-PrMgCl, is
Elena Petit et al.
The Journal of organic chemistry, 79(18), 8826-8834 (2014-08-28)
The use of the 2-(4-methylphenylsulfonyl)ethenyl (tosvinyl, Tsv) group for the protection of the NH group of a series of imides, azinones (including AZT), inosines, and cyclic sulfonamides has been examined. The Tsv-protected derivatives are obtained in excellent yields by conjugate
A Simplified Method for the Preparation of Ethynyl P-Tolyl Sulfone and Ethynyl Phenyl Sulfone.
Chen Z and Trudell ML.
Synthetic Communications, 24(21), 3149-3155 (1994)
Hao Chen et al.
Bioorganic & medicinal chemistry letters, 17(7), 1979-1983 (2007-02-16)
A library of potential antifungal triazole-modified beta-methoxyacrylate analogues was designed and synthesized via a Cu(I)-catalyzed 1,3-dipolar alkyne-azide coupling reaction or 'click chemistry'. Subsequent biological screening revealed that some compounds displayed low to moderate antifungal activity toward pathogenic fungi and low

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service