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Sigma-Aldrich

2-Amino-4-phenylphenol

technical grade, 90%

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About This Item

Linear Formula:
H2NC6H3(C6H5)OH
CAS Number:
1134-36-7
Molecular Weight:
185.22
EC Number:
214-484-8
MDL number:
MFCD00059187
UNSPSC Code:
12352100
PubChem Substance ID:
24864568
NACRES:
NA.22

grade

technical grade

assay

90%

form

powder

mp

198-202 °C (lit.)

SMILES string

Nc1cc(ccc1O)-c2ccccc2

InChI

1S/C12H11NO/c13-11-8-10(6-7-12(11)14)9-4-2-1-3-5-9/h1-8,14H,13H2

InChI key

IGIDZGNPFWGICD-UHFFFAOYSA-N

General description

2-Amino-4-phenylphenol is an aminoalcohol derivative. It participates in the synthesis of bisbenzoxazoles.

Application

2-Amino-4-phenylphenol is suitable as an internal standard to investigate the enzymatic activity of N-hydroxy-N-2-fluorenylacetamide (N-OH-2-FAA), a mammary gland carcinogen in the female Sprague-Dawley rat, by HPLC.
It may be used as a chelating agent for metal ions.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Metal ion complexing properties of carcinogen metabolites.
J H WEISBURGER et al.
Biochemical pharmacology, 12, 179-191 (1963-02-01)
Synthesis and properties of 4, 4'-bis [5-alkyl (aryl) benzoxazol-2-yl]-2-hydroxy (alkoxy) biphenyls.
Ol'khovik VK, et al.
Russ. J. Org. Chem., 42(8), 1164-1168 (2006)
C L Ritter et al.
Carcinogenesis, 17(11), 2411-2418 (1996-11-01)
N-Hydroxy-N-2-fluorenylacetamide (N-OH-2-FAA) and its benzamide analogue N-OH-2-FBA are mammary gland carcinogens in the female Sprague-Dawley rat. Ovariectomy inhibits tumorigenicity of topically applied N-OH-2-FAA suggesting modulation of carcinogen-activating enzymes in the gland. This study concerned the activation of N-OH-2-FAA and N-OH-2-FBA

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