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Sigma-Aldrich

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide

≥97.0% (T), for peptide synthesis

Synonym(s):

N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide, EDC, WSC

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About This Item

Empirical Formula (Hill Notation):
C8H17N3
CAS Number:
1892-57-5
Molecular Weight:
155.24
Beilstein/REAXYS Number:
507429
EC Number:
217-579-2
MDL number:
MFCD00044916
UNSPSC Code:
12352116
PubChem Substance ID:
57649895
NACRES:
NA.22

product name

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide, ≥97.0% (T)

assay

≥97.0% (T)

form

liquid

reaction suitability

reaction type: Coupling Reactions

refractive index

n20/D 1.461

density

0.877 g/mL at 20 °C (lit.)

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

CCN=C=NCCCN(C)C

InChI

1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3

InChI key

LMDZBCPBFSXMTL-UHFFFAOYSA-N

General description

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide is commonly used in combination with N-hydroxysuccinimide (NHS) in carbodiimide coupling reaction to activate carboxyl group for coupling with amines to form amides.

Application

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide has been used for the surface functionalization of graphene quantum dots (GQDs) employed as sensing probes in Janus micromotors to detect enterobacterial contamination. It has also been used for the activation of folic acid, prior to its conjugation on silica nanoparticles.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1A - STOT RE 2 Oral

target_organs

Stomach,large intestine,lymph node

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

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