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Sigma-Aldrich

3-Aminopropyl-functionalized silica gel

40-63 μm, extent of labeling: ~1 mmol/g NH2 loading

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About This Item

MDL number:
MFCD00132846
UNSPSC Code:
12352309
PubChem Substance ID:
24862420
NACRES:
NA.22

form

powder

extent of labeling

~1 mmol/g NH2 loading
~9% functionalized

surface area

550 m2/g

matrix

irregular silica particle platform

matrix active group

NH2 phase

particle size

40-63 μm

pore size

60 Å pore size

SMILES string

O[SiH3].CCCN

General description

The product is silica gel functionalized with amino groups. The product (3-Aminopropyl-functionalized silica gel) is 9% functionalized and has 1mmol/g of NH2 loading (extent of labelling). It participates as catalyst in the Knoevenagel condensation reactions.

Application

3-Aminopropyl-functionalized silica gel may be used in the following studies:
  • For the separation of polychlorinated biphenyls (PCBs) from lipids by combined supercritical fluid extraction and separation.
  • Preparation of the tin complex immobilized on silica gel, a novel, green, highly efficient and heterogeneous reusable catalyst.
  • Preparation of silica gel bearing isonicotinamide groups.
  • Synthesis of a novel catalytic system including Pd(OAc)2 attached to a bis(oxazoline) ligand that is covalently bonded to 3-mercaptopropyl-functionalized silica gel.
  • Useful as a heterogeneous, reusable catalyst for the Knoevenagel condensation.
  • For low- and medium-pressure reversed-phase liquid chromatography.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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3-Carboxypropyl, functionalized silica gel 200-400 mesh

Sigma-Aldrich

569836

3-Carboxypropyl, functionalized silica gel

H Gruber-Woelfler et al.
Journal of catalysis, 286(9), 30-40 (2012-08-10)
The synthesis and characterization of a novel catalytic system including Pd(OAc)(2) attached to a bis(oxazoline) (=BOX) ligand that is covalently bonded to 3-mercaptopropyl-functionalized silica gel is presented. The catalyst was tested for Suzuki-Miyaura reactions of different aryl halides with phenylboronic
Ramin Ghahremanzadeh et al.
Dalton transactions (Cambridge, England : 2003), 43(42), 15791-15797 (2014-09-13)
In the present study, a tin complex immobilized on silica gel as a novel, green, highly efficient and heterogeneous reusable catalyst was synthesized by grafting 2-amino benzamide onto the silica gel surface as a result of the reaction between isatoic
E G Alley et al.
Journal of AOAC International, 78(4), 1051-1054 (1995-07-01)
We present a method that combines the extraction of polychlorinated biphenyls (PCBs) and their separation from relatively large quantities of fat in biological matrixes by combined supercritical fluid extraction and separation. Cyano-functionalized silica gel, silica gel, aluminum oxide, Florisil, 3-amino-propyl-functionalized
Journal of the Chemical Society. Perkin Transactions 1, 105-105 (1989)
Amino groups immobilized on silica gel: an efficient and reusable heterogeneous catalyst for the Knoevenagel condensation.
Angeletti E, et al.
Journal of the Chemical Society. Perkin Transactions 1, 1, 105-107 (1989)
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Articles

Functionalized Silica Gels for Organic Synthesis

Functionalized silica gel is used in size-exclusion chromatography of cationic polymers and in the separation of sugars, steroids, cholesterol, and triglycerides.

Knoevenagel Condensation Reaction

Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.

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