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317306

Sigma-Aldrich

3,3′-Iminodipropionitrile

technical grade, 90%

Synonym(s):

Bis(2-cyanoethyl)amine

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About This Item

Linear Formula:
HN(CH2CH2CN)2
CAS Number:
111-94-4
Molecular Weight:
123.16
EC Number:
203-922-3
MDL number:
MFCD00001956
UNSPSC Code:
12352100
PubChem Substance ID:
24859071
NACRES:
NA.22

grade

technical grade

assay

90%

form

liquid

refractive index

n20/D 1.47 (lit.)

bp

205 °C/25 mmHg (lit.)

density

1.02 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

N#CCCNCCC#N

InChI

1S/C6H9N3/c7-3-1-5-9-6-2-4-8/h9H,1-2,5-6H2

InChI key

SBAJRGRUGUQKAF-UHFFFAOYSA-N

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCT2980
0000184986
0000200109
MKCS1170
MKCQ7854

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Ana Seoane et al.
Acta neuropathologica, 106(5), 458-470 (2003-08-05)
3,3'-Iminodipropionitrile (IDPN) is a neurotoxic compound that causes both a proximal neurofilamentous axonopathy and loss of the vestibular sensory hair cells. We used immunocytochemistry to examine changes in the expression of heavy, medium and light neurofilament (NF-H, NF-M, NF-L) proteins
Henrik A Hartmann
Neurotoxicology, 26(2), 277-283 (2005-02-17)
Iminodipropionitrile (IDPN) was given to rats on diets with normal copper levels, 5 ppm, and to rats on diets with high copper levels, 100 ppm. The former developed neurological symptoms, namely choreoathetoid head movements, circling and retropulsion, while the latter
Does copper ameliorate the vestibular toxicity of iminodipropionitrile (IDPN)?
J Llorens
Neurotoxicology, 26(3), 475-476 (2005-05-12)
C Schlecker et al.
Gene therapy, 18(9), 884-890 (2011-04-08)
Loss of balance is often due to loss of vestibular hair cells. In mammals, regeneration of functional hair cells in the mature sensory epithelium is limited; therefore, loss of sensory cells can lead to debilitating balance problems. Delivery of the
Haseeb Ahmad Khan
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 64(7-8), 791-796 (2011-03-11)
Exposure of iminodipropionitrile (IDPN) to rodents produces permanent behavioral syndrome characterized by repetitive head movements, circling and back walking. Other synthetic nitriles of industrial importance such as crotonitrile and allylnitrile are also able to produce similar motor deficits in experimental
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