Skip to Content
MilliporeSigma
All Photos(1)

Documents

275271

Sigma-Aldrich

3,7-Dihydroxy-2-naphthoic acid

95%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(HO)2C10H5CO2H
CAS Number:
83511-07-3
Molecular Weight:
204.18
Beilstein/REAXYS Number:
3288005
MDL number:
MFCD00010253
UNSPSC Code:
12352100
PubChem Substance ID:
24856639
NACRES:
NA.22

assay

95%

form

powder

mp

265 °C±10 °C (dec.) (lit.)

SMILES string

OC(=O)c1cc2cc(O)ccc2cc1O

InChI

1S/C11H8O4/c12-8-2-1-6-5-10(13)9(11(14)15)4-7(6)3-8/h1-5,12-13H,(H,14,15)

InChI key

QMWOUSYSNFCKAZ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

3,7-Dihydroxy-2-naphthoic acid served as a substrate for the enzyme NcsB1 (an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin) in the NcsB1-catalyzed O-methylation of 2,7-dihydroxy-5-methyl-1-naphthoic acid.

Application

3,7-Dihydroxy-2-naphthoic acid was used in the synthesis of 3-hydroxy-7-methoxy-2-naphthoic acid.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Yinggang Luo et al.
The Journal of biological chemistry, 283(21), 14694-14702 (2008-04-05)
Neocarzinostatin, a clinical anticancer drug, is the archetypal member of the chromoprotein family of enediyne antitumor antibiotics that are composed of a nonprotein chromophore and an apoprotein. The neocarzinostatin chromophore consists of a nine-membered enediyne core, a deoxyaminosugar, and a

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service