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205494

Sigma-Aldrich

Dibutyltin dichloride

96%

Synonym(s):

Dibutyldichlorotin

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About This Item

Linear Formula:
(CH3CH2CH2CH2)2SnCl2
CAS Number:
683-18-1
Molecular Weight:
303.84
Beilstein/REAXYS Number:
3535484
EC Number:
211-670-0
MDL number:
MFCD00000518
UNSPSC Code:
12352103
PubChem Substance ID:
24852336
NACRES:
NA.22

assay

96%

form

solid

bp

135 °C/10 mmHg (lit.)

mp

37-40 °C (lit.)

SMILES string

CCCC[Sn](Cl)(Cl)CCCC

InChI

1S/2C4H9.2ClH.Sn/c2*1-3-4-2;;;/h2*1,3-4H2,2H3;2*1H;/q;;;;+2/p-2

InChI key

RJGHQTVXGKYATR-UHFFFAOYSA-L

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Application

  • Effects of dibutyltin compounds on PPARγ/RXRα activity: Studies the impact of various dibutyltin compounds, including dibutyltin dichloride, on adipogenesis and inflammation in mammalian cells, emphasizing their effects on the PPARγ/RXRα pathway (Milton et al., 2017).

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Muta. 2 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1 - STOT RE 1 Oral - STOT SE 1 Oral

target_organs

thymus

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
SHBQ1704
SHBQ4379
SHBQ2566
MKCP3017
SHBJ2721

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Activated pancreatic stellate cells (PSCs) play an important role in pancreatic fibrosis and inflammation, where oxidative stress is implicated in the pathogenesis. NADPH oxidase might be a source of reactive oxygen species (ROS) in the injured pancreas. This study aimed
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