166782

2,2′-Thiodiethanol

≥99%

• Synonym(s): 2,2′-Thiobis(ethanol), Bis(2-hydroxyethyl) sulfide, Thiodiethylene glycol, Thiodiglycol
• Linear Formula: S(CH₂CH₂OH)₂
• CAS Number: 111-48-8
• Molecular Weight: 122.19
• Beilstein/REAXYS Number: 1236325
• EC Number: 203-874-3
• MDL number: MFCD00002910
• UNSPSC Code: 12352100
• PubChem Substance ID: 24850185
• NACRES: NA.22

Properties

• Quality Level: 200
• assay: ≥99%
• form: liquid
• refractive index: n20/D 1.5215 (lit.)
• bp: 164-166 °C/20 mmHg (lit.)
• mp: −16 °C (lit.)
• solubility: alcohol: miscible(lit.); diethyl ether: slightly soluble(lit.); water: miscible(lit.)
• density: 1.221 g/mL at 25 °C (lit.)
• functional group: hydroxyl; thioether
• SMILES string: OCCSCCO
• InChI: 1S/C4H10O2S/c5-1-3-7-4-2-6/h5-6H,1-4H2
• InChI key: YODZTKMDCQEPHD-UHFFFAOYSA-N

Description

General description

2,2′-Thiodiethanol (TDE), also known as bis(2-hydroxyethyl)sulfide and thiodiglycol, is commonly used as a solvent in organic synthesis. It is a nontoxic, water soluble embedding medium for optical microscopy. It is the hydrolysis product of sulfur mustard.

Application

2,2′-Thiodiethanol can be used:

• In the synthesis of luminescent polynuclear gold(I) phosphine complexes.
• To prepare Co(II) and Mn(II) complexes.
• As a reactant to prepare sulfone-containing polyurethane materials for electrophoretic applications.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: 329.0 °F
• flash_point_c: 165 °C
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter