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158348

Sigma-Aldrich

4-(Benzyloxy)phenol

98%

Synonym(s):

4-(Phenylmethoxy)phenol, Hydroquinone monobenzyl ether

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25 G
$51.40
100 G
$135.00

About This Item

Linear Formula:
C6H5CH2OC6H4OH
CAS Number:
Molecular Weight:
200.23
Beilstein/REAXYS Number:
1958305
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

$51.40


Available to ship onApril 15, 2025Details


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Quality Level

assay

98%

form

solid

mp

119-120 °C (lit.)

functional group

phenyl

SMILES string

Oc1ccc(OCc2ccccc2)cc1

InChI

1S/C13H12O2/c14-12-6-8-13(9-7-12)15-10-11-4-2-1-3-5-11/h1-9,14H,10H2

InChI key

VYQNWZOUAUKGHI-UHFFFAOYSA-N

Gene Information

human ... TYR(7299)
rat ... Ar(24208)

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Application

4-(Benzyloxy)phenol was used in the synthesis of bis(4-benzyloxyphenoxy)phenyl phosphine oxide.[1] It was also used in the preparation of series of hetaryl-azophenol dyes via heterocyclic amines in nitrosyl sulphuric acid.[2]

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Synthesis, spectral properties, biological activity and application of new 4-(benzyloxy) phenol derived azo dyes for polyester fiber dyeing.
Yousefi H, et al.
Journal of Molecular Liquids, 180, 51-58 (2013)
Jasper G van den Boorn et al.
The Journal of investigative dermatology, 131(6), 1240-1251 (2011-02-18)
In this study, we report the previously unknown mechanism of inducing robust anti-melanoma immunity by the vitiligo-inducing compound monobenzone. We show monobenzone to increase melanocyte and melanoma cell immunogenicity by forming quinone-haptens to the tyrosinase protein and by inducing the
Contact hypersensitivity to monobenzyl ether of hydroquinone used to treat vitiligo.
C C Lyon et al.
Contact dermatitis, 39(3), 132-133 (1998-10-15)
Jasper G van den Boorn et al.
PloS one, 5(5), e10626-e10626 (2010-05-26)
Presently melanoma still lacks adequate treatment options for metastatic disease. While melanoma is exceptionally challenging to standard regimens, it is suited for treatment with immunotherapy based on its immunogenicity. Since treatment-related skin depigmentation is considered a favourable prognostic sign during
Synthesis, characterization and thermal degradation of functional benzoxazine monomers and polymers containing phenylphosphine oxide.
Choi S-W, et al.
Polymer Degradation and Stability, 91(5), 1166-1178 (2006)

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