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assay
97%
mp
92-94 °C (lit.)
SMILES string
[O-][N+](=O)c1ccc2NCCc2c1
InChI
1S/C8H8N2O2/c11-10(12)7-1-2-8-6(5-7)3-4-9-8/h1-2,5,9H,3-4H2
InChI key
WJQWYAJTPPYORB-UHFFFAOYSA-N
Application
5-Nitroindoline was used to prepare acetylated glucosylamines using the Suvorov procedure.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Journal of medicinal chemistry, 63(1), 163-185 (2019-12-10)
Kv7 K+ channels represent attractive pharmacological targets for the treatment of different neurological disorders, including epilepsy. In this paper, 42 conformationally restricted analogues of the prototypical Kv7 activator retigabine have been synthesized and tested by electrophysiological patch-clamp experiments as Kv7
Substituted glucosylamines containing the indole nucleus.
Tetrahedron, 25(18), 4543-4550 (1969)
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