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130214

Sigma-Aldrich

5-Nitroindoline

97%

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About This Item

Empirical Formula (Hill Notation):
C8H8N2O2
CAS Number:
Molecular Weight:
164.16
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

assay

97%

mp

92-94 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc2NCCc2c1

InChI

1S/C8H8N2O2/c11-10(12)7-1-2-8-6(5-7)3-4-9-8/h1-2,5,9H,3-4H2

InChI key

WJQWYAJTPPYORB-UHFFFAOYSA-N

Application

5-Nitroindoline was used to prepare acetylated glucosylamines using the Suvorov procedure.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Carmine Ostacolo et al.
Journal of medicinal chemistry, 63(1), 163-185 (2019-12-10)
Kv7 K+ channels represent attractive pharmacological targets for the treatment of different neurological disorders, including epilepsy. In this paper, 42 conformationally restricted analogues of the prototypical Kv7 activator retigabine have been synthesized and tested by electrophysiological patch-clamp experiments as Kv7
Substituted glucosylamines containing the indole nucleus.
Magnin AA, et al.
Tetrahedron, 25(18), 4543-4550 (1969)

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