100536

4-Aminobenzoic acid

99%, for peptide synthesis, ReagentPlus^®

• Synonym(s): PABA, Vitamin B_x, Vitamin H₁
• Linear Formula: H₂NC₆H₄CO₂H
• CAS Number: 150-13-0
• Molecular Weight: 137.14
• Beilstein/REAXYS Number: 471605
• EC Number: 205-753-0
• MDL number: MFCD00007894
• UNSPSC Code: 12352106
• eCl@ss: 32160406
• PubChem Substance ID: 22435039
• NACRES: NA.22

Properties

• product name: 4-Aminobenzoic acid, ReagentPlus^®, 99%
• Quality Level: 200
• product line: ReagentPlus^®
• assay: 99%
• form: solid
• reaction suitability: reaction type: solution phase peptide synthesis
• mp: 187-189 °C (lit.)
• solubility: 95% ethanol: soluble 5%, clear to slightly hazy, colorless to yellow
• density: 1.374 g/mL at 25 °C (lit.)
• application(s): peptide synthesis
• SMILES string: Nc1ccc(cc1)C(O)=O
• InChI: 1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
• InChI key: ALYNCZNDIQEVRV-UHFFFAOYSA-N

Description

General description

4-Aminobenzoic acid (4-ABA) acts as an bacterial cofactor and participates in the synthesis of folic acid. It is a versatile reagent for structure extension through linear hydrogen-bonding associations, involving both the carboxylic acid and amine functional groups. Formation of 4-ABA monolayer film on glassy carbon electrode (GCE) by amino cation radical method has been described. Molecular adducts of 4-ABA have been prepared and their characterization by infrared spectroscopy and X-ray diffration methods have been reported.

Application

4-Aminobenzoic acid may be used in the following studies:

• Covalent modification of glassy carbon electrode.
• Synthesis of 1,4-(2-chlorobenzylidene)aminobenzoic acid (Schiff base).
• Spectrophotometric determination of the trace amounts of dopamine, methyldopa and levodopa.
• Synthesis of 1:1 proton-transfer compound with 5-sulfosalicylic acid.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• hcodes: H412
• pcodes: P273 - P501
• Hazard Classifications: Aquatic Chronic 3
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: 339.8 °F - closed cup
• flash_point_c: 171 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves