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RGS1

regulator of G-protein signaling 1

Synonyms:
1R20, BL34, IER1, IR20
Species:
UniProtKB ID:
Gene ID:
  • Human(5996) Summary: This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]
  • Mouse(50778) regulator of G-protein signaling 1
  • Rat(54289) regulator of G-protein signaling 1
  • domestic guinea pig(100715338) regulator of G-protein signaling 1
  • naked mole-rat(101701218) regulator of G-protein signaling 1
  • cow(540836) regulator of G-protein signaling 1
  • chicken(424360) regulator of G-protein signaling 1
  • Zebrafish(556179) regulator of G-protein signaling 1
  • Thale Cress(822207) putative membrane receptor protein RGS1
  • domestic cat(101088975) regulator of G-protein signaling 1
  • dog(488585) regulator of G-protein signaling 1
  • sheep(101122711) regulator of G-protein signaling 1
  • Horse(100034151) regulator of G-protein signaling 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-RGS1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, mouse
Application
western blot
Anti-RGS1/1R20 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
western blot
Anti-RGS1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-RGS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

Proteins

Product Number
Description
Species
RGS1, His tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human RGS1,
Species
human
MISSION® esiRNA, targeting mouse Rgs1,
Species
mouse