GLE1
GLE1 RNA export mediator
Synonyms:
GLE1L, LCCS, LCCS1, hGLE1
Species:
Human GLE1 (2733), Mouse Gle1 (74412), Rat Gle1 (362098), sheep GLE1 (101119123), Horse GLE1 (100066964), domestic guinea pig Gle1 (100732111), naked mole-rat Gle1 (101722063), cow GLE1 (540982), chicken GLE1 (417212), Zebrafish gle1 (445408) ...More
UniProtKB ID:
Gene ID:
- Human(2733) Summary: This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(74412) GLE1 RNA export mediator (yeast)
- Rat(362098) GLE1 RNA export mediator
- sheep(101119123) GLE1 RNA export mediator homolog (yeast)
- Horse(100066964) GLE1 RNA export mediator homolog (yeast)
- domestic guinea pig(100732111) GLE1 RNA export mediator
- naked mole-rat(101722063) GLE1 RNA export mediator homolog (yeast)
- cow(540982) GLE1 RNA export mediator homolog (yeast)
- chicken(417212) GLE1 RNA export mediator
- Zebrafish(445408) GLE1 RNA export mediator homolog (yeast)
- dog(480704) GLE1 RNA export mediator homolog (yeast)
- domestic cat(101080492) GLE1 RNA export mediator homolog (yeast)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GLE1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-GLE1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
horse, human, rat
Application
western blot
Anti-GLE1L antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-GLE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-GLE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence