EP300
E1A binding protein p300
Synonyms:
KAT3B, RSTS2, p300
Species:
Human EP300 (2033), Mouse Ep300 (328572), Rat Ep300 (170915), dog EP300 (100684945), domestic guinea pig Ep300 (100734820), chicken EP300 (418000), domestic cat EP300 (101088344), naked mole-rat Ep300 (101711512), Horse EP300 (100055626), sheep EP300 (101110136)
UniProtKB ID:
Gene ID:
- Human(2033) Summary: This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
- Mouse(328572) E1A binding protein p300
- Rat(170915) E1A binding protein p300
- dog(100684945) E1A binding protein p300
- domestic guinea pig(100734820) E1A binding protein p300
- chicken(418000) E1A binding protein p300
- domestic cat(101088344) E1A binding protein p300
- naked mole-rat(101711512) E1A binding protein p300
- Horse(100055626) E1A binding protein p300
- sheep(101110136) E1A binding protein p300
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-EP300 antibody produced in mouse, clone 1B1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-EP300 antibody produced in mouse, clone 1D2, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-p300 CT Antibody, clone RW128, clone RW128, Upstate®, from mouse,
Species Reactivity
human, mouse, rat
Application
ChIP
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-EP300 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-P300 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species
p300 (C1135-2414) human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Species
human
P300 (1283-1673), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
p300, HAT Domain, Recombinant GST-fusion protein corresponding to amino acids 1066-1707 of human p300.,
Species
human