CSTB
cystatin B (stefin B)
Synonyms:
CST6, EPM1, EPM1A, PME, STFB, ULD
Species:
Human CSTB (1476), Mouse Cstb (13014), Rat Cstb (25308), domestic guinea pig Cstb (100719016), naked mole-rat Cstb (101699171), cow CSTB (514170), cow CSTB (512805), dog CSTB (478424), chicken CSTB (418267), sheep CSTB (101123265)
UniProtKB ID:
Gene ID:
- Human(1476) Summary: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). [provided by RefSeq, Jul 2008]
- Mouse(13014) cystatin B
- Rat(25308) cystatin B (stefin B)
- domestic guinea pig(100719016) cystatin B (stefin B)
- naked mole-rat(101699171) cystatin B (stefin B)
- cow(514170) cystatin B (stefin B)
- cow(512805) cystatin B (stefin B)
- dog(478424) cystatin B (stefin B)
- chicken(418267) cystatin B (stefin B)
- sheep(101123265) cystatin B (stefin B)
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CSTB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-CSTB antibody produced in mouse, clone M1-C1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-CSTB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Proteins
Product Number
Description
Species