Skip to Content
MilliporeSigma

CFL1

cofilin 1 (non-muscle)

Synonyms:
CFL
Species:
UniProtKB ID:
Gene ID:
  • Human(1072) Summary: The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
  • Mouse(12631) cofilin 1, non-muscle
  • Rat(29271) cofilin 1, non-muscle
  • sheep(494432) cofilin 1 (non-muscle)
  • dog(476022) cofilin 1 (non-muscle)
  • Zebrafish(406738) cofilin 1 (non-muscle)
  • cow(534553) cofilin 1 (non-muscle)
  • naked mole-rat(101713836) cofilin 1 (non-muscle)
  • domestic cat(101100251) cofilin 1 (non-muscle)
  • domestic guinea pig(100732287) cofilin 1 (non-muscle)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-CFL1 (pTyr139) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
Anti-Phospho-CFL1-S3 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-Cfl1 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
Anti-p-Cofilin (Ser3) Antibody, clone 5L4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
hamster, human, mouse, rat
Application
immunocytochemistry
inhibition assay

western blot
Anti-CFL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
Cofilin 1 Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human