APEH
acylaminoacyl-peptide hydrolase
Synonyms:
AARE, ACPH, APH, D3F15S2, D3S48E, DNF15S2, OPH
Species:
Human APEH (327), Mouse Apeh (235606), Rat Apeh (24206), Zebrafish apeh (321028), sheep APEH (101103273), chicken APEH (415926), Domestic Rabbit APEH (100354109), cow APEH (514666), dog APEH (476622), Horse APEH (100053100) ...More
UniProtKB ID:
Gene ID:
- Human(327) Summary: This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. [provided by RefSeq, Jul 2008]
- Mouse(235606) acylpeptide hydrolase
- Rat(24206) acylaminoacyl-peptide hydrolase
- Zebrafish(321028) acylpeptide hydrolase
- sheep(101103273) N-acylaminoacyl-peptide hydrolase
- chicken(415926) N-acylaminoacyl-peptide hydrolase
- Domestic Rabbit(100354109) N-acylaminoacyl-peptide hydrolase
- cow(514666) N-acylaminoacyl-peptide hydrolase
- dog(476622) N-acylaminoacyl-peptide hydrolase
- Horse(100053100) N-acylaminoacyl-peptide hydrolase
- naked mole-rat(101715825) acylaminoacyl-peptide hydrolase
- domestic cat(101085867) N-acylaminoacyl-peptide hydrolase
- domestic guinea pig(100730493) acylaminoacyl-peptide hydrolase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-APEH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab4,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-APEH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab3,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-APEH antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot