RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
Synonyms:
GFR, MR-GEF, REPAC
Species:
Human RAPGEF5 (9771), Mouse Rapgef5 (217944), Rat Rapgef5 (362799), domestic guinea pig Rapgef5 (100733128), dog RAPGEF5 (482349), Domestic Rabbit RAPGEF5 (100337732), chicken RAPGEF5 (100857462), naked mole-rat Rapgef5 (101700232), Horse RAPGEF5 (100067593), cow RAPGEF5 (519566) ...More
UniProtKB ID:
Gene ID:
- Human(9771) Summary: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]
- Mouse(217944) Rap guanine nucleotide exchange factor (GEF) 5
- Rat(362799) Rap guanine nucleotide exchange factor (GEF) 5
- domestic guinea pig(100733128) Rap guanine nucleotide exchange factor (GEF) 5
- dog(482349) Rap guanine nucleotide exchange factor (GEF) 5
- Domestic Rabbit(100337732) Rap guanine nucleotide exchange factor (GEF) 5
- chicken(100857462) Rap guanine nucleotide exchange factor (GEF) 5
- naked mole-rat(101700232) Rap guanine nucleotide exchange factor (GEF) 5
- Horse(100067593) Rap guanine nucleotide exchange factor (GEF) 5
- cow(519566) Rap guanine nucleotide exchange factor (GEF) 5
- sheep(101108303) Rap guanine nucleotide exchange factor (GEF) 5
- domestic cat(101088478) Rap guanine nucleotide exchange factor (GEF) 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RAPGEF5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-RAPGEF5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-RAPGEF5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-RAPGEF5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-RAPGEF5 antibody produced in mouse, clone 2E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot