PTPRN
protein tyrosine phosphatase, receptor type, N
Synonyms:
IA-2, IA-2/PTP, IA2, ICA512, R-PTP-N
Species:
Human PTPRN (5798), Mouse Ptprn (19275), Rat Ptprn (116660), Domestic Rabbit PTPRN (100355368), domestic cat PTPRN (101100657), dog PTPRN (478921), cow PTPRN (286810), sheep PTPRN (101113312), domestic guinea pig Ptprn (100733759), naked mole-rat Ptprn (101718650)
UniProtKB ID:
Gene ID:
- Human(5798) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
- Mouse(19275) protein tyrosine phosphatase, receptor type, N
- Rat(116660) protein tyrosine phosphatase, receptor type, N
- Domestic Rabbit(100355368) protein tyrosine phosphatase, receptor type, N
- domestic cat(101100657) protein tyrosine phosphatase, receptor type, N
- dog(478921) protein tyrosine phosphatase, receptor type, N
- cow(286810) protein tyrosine phosphatase, receptor type, N
- sheep(101113312) protein tyrosine phosphatase, receptor type, N
- domestic guinea pig(100733759) protein tyrosine phosphatase, receptor type, N
- naked mole-rat(101718650) protein tyrosine phosphatase, receptor type, N
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PTPRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-PTPRN antibody produced in mouse, clone 8E3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-PTPRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ICA 512/RESP18 Antibody, clone 1348-D29-1, ,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-IA2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Proteins
Product Number
Description
Species