DPM2
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
Synonyms:
CDG1U
Species:
Human DPM2 (8818), Mouse Dpm2 (13481), Rat Dpm2 (29640), domestic cat DPM2 (101098016), cow DPM2 (523737), Zebrafish dpm2 (796295), chicken DPM2 (771539), domestic guinea pig Dpm2 (100725474), naked mole-rat Dpm2 (101716252), sheep DPM2 (101122767)
UniProtKB ID:
Gene ID:
- Human(8818) Summary: Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. [provided by RefSeq, Jul 2008]
- Mouse(13481) dolichol-phosphate (beta-D) mannosyltransferase 2
- Rat(29640) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- domestic cat(101098016) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- cow(523737) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- Zebrafish(796295) dolichol-phosphate (beta-D) mannosyltransferase 2
- chicken(771539) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- domestic guinea pig(100725474) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- naked mole-rat(101716252) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- sheep(101122767) dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DPM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry