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Key Documents

S3875

Sigma-Aldrich

Seleno-DL-methionine

≥99% (TLC)

Synonym(s):

2-amino-4-(methylseleno)-Butanoic acid

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About This Item

Empirical Formula (Hill Notation):
C5H11NO2Se
CAS Number:
Molecular Weight:
196.11
Beilstein:
1758204
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26

product name

Seleno-DL-methionine, ≥99% (TLC)

Assay

≥99% (TLC)

form

powder

color

white to off-white

application(s)

cell analysis

storage temp.

−20°C

SMILES string

C[Se]CCC(N)C(O)=O

InChI

1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

InChI key

RJFAYQIBOAGBLC-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Qun Liu et al.
Science (New York, N.Y.), 336(6084), 1033-1037 (2012-05-26)
Crystal structure analyses for biological macromolecules without known structural relatives entail solving the crystallographic phase problem. Typical de novo phase evaluations depend on incorporating heavier atoms than those found natively; most commonly, multi- or single-wavelength anomalous diffraction (MAD or SAD)
Jiankun Duan et al.
Journal of chromatography. A, 1268, 173-179 (2012-11-13)
A new phenylalanine derivative (L-N-(2-hydroxy-propyl)-phenylalanine, L-HP-Phe) was synthesized and its chelate with Cu(II) (Cu(II)-(L-HP-Phe)(2)) was used as the chiral selector for the ligand-exchange (LE) chiral separation of D,L-selenomethionine (SeMet) in selenized yeast samples by micelle electrokinetic capillary chromatography (MEKC). In
Ian R Bothwell et al.
Journal of the American Chemical Society, 134(36), 14905-14912 (2012-08-25)
Posttranslational methylation by S-adenosyl-L-methionine(SAM)-dependent methyltransferases plays essential roles in modulating protein function in both normal and disease states. As such, there is a growing need to develop chemical reporters to examine the physiological and pathological roles of protein methyltransferases. Several
Vasundara Venkateswaran et al.
Cancer research, 62(9), 2540-2545 (2002-05-01)
Prostate cancer (PCA) is the most common histological malignancy and the second leading cause of cancer deaths among North American men. There has been considerable interest in the chemopreventative properties of selenium. In this study, we assessed whether selenium inhibits
Pedro José Barbosa Pereira et al.
Journal of structural biology, 181(2), 89-94 (2012-11-28)
Selenomethionine labeling is the most common technique used in protein crystallography to derivatize recombinant proteins for experimental phasing using anomalous scattering at tunable synchrotron beamlines. Recently, it has been shown that UV radiation depletes electron density of selenium atoms of

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