Skip to Content
Merck
All Photos(1)

Key Documents

PZ0140

Sigma-Aldrich

EBPC

≥98% (HPLC)

Synonym(s):

2,5-Dihydro-4-hydroxy-5-oxo-1-(phenylmethyl)-1H-pyrrole-3-carboxylic acid ethyl ester, CP-10668

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C14H15NO4
CAS Number:
Molecular Weight:
261.27
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

white

solubility

DMSO: ≥10 mg/mL

storage temp.

room temp

SMILES string

CCOC(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1

InChI

1S/C14H15NO4/c1-2-19-14(18)11-9-15(13(17)12(11)16)8-10-6-4-3-5-7-10/h3-7,16H,2,8-9H2,1H3

InChI key

IGYRPDIWSYGHMY-UHFFFAOYSA-N

Biochem/physiol Actions

EBPC is an aldose reductase inhibitor; anti-cancer.

Other Notes

air sensitive

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Eva Bresson et al.
Frontiers in pharmacology, 3, 98-98 (2012-06-02)
Prostaglandins are important regulators of female reproductive functions to which aldose reductases exhibiting hydroxysteroid dehydrogenase activity also contribute. Our work on the regulation of reproductive function by prostaglandins (PGs), lead us to the discovery that AKR1B5 and later AKR1B1were highly
E S Kang et al.
Cellular and molecular life sciences : CMLS, 62(10), 1146-1155 (2005-06-02)
Over-expression of aldose reductase (AR) has been observed in many cancer cells. To clarify the role of AR in tumor cells, we investigated the pathways mediating expression of the AR gene induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), a potent tumor promoter. In

Articles

Discover Bioactive Small Molecules for Lipid Signaling Research

Discover Bioactive Small Molecules for Lipid Signaling Research

Discover Bioactive Small Molecules for Lipid Signaling Research

Discover Bioactive Small Molecules for Lipid Signaling Research

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service