C1006

Cytidine 5′-monophosphate disodium salt

Sigma Grade, ≥99%, crystalline

• Synonym(s): C-5′-P, CMP
• Linear Formula: C₉H₁₂N₃O₈PNa₂
• CAS Number: 6757-06-8
• Molecular Weight: 367.16
• EC Number: 229-819-3
• MDL number: MFCD00064355
• UNSPSC Code: 41106305
• PubChem Substance ID: 24892293
• NACRES: NA.51

Properties

• biological source: synthetic
• grade: Sigma Grade
• Assay: ≥99%
• form: crystalline
• solubility: water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
• storage temp.: 2-8°C
• SMILES string: [Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(O)=O)C(O)C2O
• InChI: 1S/C9H14N3O8P.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);;
• InChI key: RCIPNLSOCXMZDD-UHFFFAOYSA-N

Description

Application

Cytidine 5′-monophosphate disodium salt has been used:

• in nucleotide stock solution
• as an ectonucleotidase (ENTase) inhibitor to probe 5′-ENTase activity in cortical neurons
• in in vitro studies to estimate its effect on growth response of selected bacteria strains that dominate the piglets′ small intestine

Biochem/physiol Actions

Cytidine 5′-monophosphate (CMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.

Cytidine monophosphate (CMP) serve as a nucleotide carrier for sugars.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves