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62035

Sigma-Aldrich

Poloxamer 407

oxyethylene 71.5-74.9 %

Synonym(s):

Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol), Lutrol F 127

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352104
NACRES:
NA.25

composition

oxyethylene, 71.5-74.9%

Quality Level

impurities

≤0.25% ethylene glycol and diethylene glycol
≤0.4% total ash
≤0.75% water
≤1 ppm ethylene oxide
≤2 ppm arsenic traces
≤20 ppm heavy metals
≤5 ppm dioxan
≤5 ppm propylene oxide
50-125 ppm butylhydroxytoluene

ign. residue

≤0.30%

color

APHA: ≤120, 50/50 in CH3OH

pH

5.0-7.5 (1:40 in H2O)

solubility

10%, clear, colorless

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

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Application

Poloxamer 407 has been widely used as a thickening agent and gel binder.

Other Notes

The Poloxamer 407 grades are poloxamers from the extensive line of Pluronic® block copolymers.

Legal Information

Pluronic is a registered trademark of BASF

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Tsz Chung Lai et al.
Colloids and surfaces. B, Biointerfaces, 99, 27-37 (2011-10-18)
Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were
Houjian Gong et al.
Langmuir : the ACS journal of surfaces and colloids, 28(38), 13590-13600 (2012-09-08)
The block polyethers PEO-PPO-ph-PPO-PEO (BPE) and PPO-PEO-ph-PEO-PPO (BEP) are synthesized by anionic polymerization using bisphenol A as initiator. Compared with Pluronic P123, the aggregation behaviors of BPE and BEP at an air/water interface are investigated by the surface tension and
A N Sklifas et al.
Biofizika, 57(2), 317-324 (2012-05-19)
The adsorption abilities of the perfluorocarbon emulsion stabilized by Proxanol 268 were investigated in vitro and in vivo. In vitro, the saturation point for the blood plasma proteins was nearly reached after five minutes of incubation of the emulsion with
Jun Song et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 66(4), 792-798 (2012-07-07)
A novel method for the determination of nickel was established by ultrasonic-assisted cloud point extraction (UA-CPE) prior to flame atomic absorption spectrometry (FAAS) analysis. The nickel reacted with N,N'-bis(salicylidene)-1,2-ethanediamine (BSE) to form hydrophobic chelates, which were extracted into the micelles
Céline Durand-Gasselin et al.
Langmuir : the ACS journal of surfaces and colloids, 27(20), 12329-12335 (2011-09-29)
Aggregation of thermosensitive polymer-coated gold nanoparticles was performed in aqueous solution in the presence of a triblock copolymer poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (Pluronic P123, PEO(20)-PPO(68)-PEO(20)). The gold nanoparticles, AuNPs, which are covered by thermosensitive statistical copolymers poly(EO(x)-st-PO(y)), aggregate when the

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