41043

2,3-Oxidosqualene

≥92.0% (HPLC)

• Synonym(s): 2,3-Epoxy-2,3-dihydrosqualene, 22,23-Epoxy-2,6,10,15,19,23-hexamethyl-2,6,10,14,18-tetracosapentaene, Squalene 2,3-epoxide, Squalene 2,3-oxide
• CAS Number: 7200-26-2
• MDL number: MFCD00871184
• UNSPSC Code: 12352202
• PubChem Substance ID: 329756051
• NACRES: NA.32

Properties

• Assay: ≥92.0% (HPLC)
• storage temp.: −20°C
• SMILES string: C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C=C(/C)CC\C=C(/C)CCC1OC1(C)C
• InChI: 1S/C30H50O/c1-24(2)14-11-17-27(5)20-12-18-25(3)15-9-10-16-26(4)19-13-21-28(6)22-23-29-30(7,8)31-29/h14-16,20-21,29H,9-13,17-19,22-23H2,1-8H3/b25-15+,26-16+,27-20+,28-21+
• InChI key: QYIMSPSDBYKPPY-BANQPHDMSA-N

Description

Application

• Lanosterol synthase deficiency promotes tumor progression by orchestrating PDL1-dependent tumor immunosuppressive microenvironment.: Demonstrates how lanosterol synthase, linked to 2,3-Oxidosqualene, influences tumor environments, potentially informing cancer treatment strategies (Gao et al., 2024).


• Promiscuous Oxidosqualene Cyclases from Neoalsomitra integrifoliola Catalyzing the Formation of Tetracyclic, Pentacyclic, and Heterocyclic Triterpenes.: Investigates the versatility of oxidosqualene cyclases, which could have implications for synthetic applications of 2,3-Oxidosqualene in producing diverse triterpenes (Li et al., 2024).

Biochem/physiol Actions

2,3-Oxidosqualene is a substrate of the 2,3-oxidosqualene cyclase lanosterol synthase. 2,3-oxidosqualene cyclase has been shown to be suppressed by a high fat diet and high levels of cholesterol.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves