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09963

Sigma-Aldrich

(Hydroxypropyl)methyl cellulose

Synonym(s):

2-Hydroxypropyl methyl cellulose ether

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25

form

powder

composition

hydroxylpropoxyl content, ~9%

color

faint beige

viscosity

~15 mPa.s, 2 % in H2O(25 °C)

solubility

water: 100 mg/10 mL, clear, colorless

storage temp.

room temp

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Application

(Hydroxypropyl)methyl cellulose (HPMC), an inert viscoelastic polymer is used as an emulsifier, thickening and suspending agent similar to animal gelatin. HPMC is used in the development of controlled-delivery medicament.
Thickener for aqueous and non-aqueous systems, clear films with grease resistance, binders, lubricants, steric stabilizer and water retention aid.

Features and Benefits

Dissolves in water, undergoes reversible gelation upon heating, non-ionic, does not complex with ionic species and is surface active and enzyme resistant. Solutions are pseudoplastic.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Lucas Sievens-Figueroa et al.
International journal of pharmaceutics, 423(2), 496-508 (2011-12-20)
The design and feasibility of a simple process of incorporating stable nanoparticles into edible polymer films is demonstrated with the goal of enhancing the dissolution rate of poorly water soluble drugs. Nanosuspensions produced from wet stirred media milling (WSMM) were
Punit P Shah et al.
Biomaterials, 33(5), 1607-1617 (2011-11-29)
The aim of this study was to develop an effective drug delivery system for the simultaneous topical delivery of two anti-inflammatory drugs, spantide II (SP) and ketoprofen (KP). To achieve this primary goal, we have developed a skin permeating nanogel
Michelle Lay Teng Ang et al.
Infection and immunity, 82(5), 1850-1859 (2014-02-26)
Tuberculosis remains a major worldwide epidemic because of its sole etiological agent, Mycobacterium tuberculosis. Ethionamide (ETH) is one of the major antitubercular drugs used to treat infections with multidrug-resistant M. tuberculosis strains. ETH is a prodrug that requires activation within
Somayeh Bahrami et al.
Veterinary parasitology, 203(1-2), 43-50 (2014-03-19)
Fasciola gigantica is a parasitic helminth that predominantly infects the liver and bile ducts of cattle and causes great losses of cattle production in the southwestern regions of Iran. The purpose of the present study was to find out the
Jeonghoon Han et al.
Aquatic toxicology (Amsterdam, Netherlands), 152, 308-317 (2014-05-13)
In this study, we investigated the effects of the water-accommodated fraction (WAF) of crude oil on the development and reproduction of the intertidal copepod Tigriopus japonicus through life-cycle experiments. Furthermore, we investigated the mechanisms underlying the toxic effects of WAF

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