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S5631

Sigma-Aldrich

Silicon dioxide

~99%, 0.5-10 μm (approx. 80% between 1-5 μm)

Synonym(s):

Sand, white quartz, Quartz, Silicon dioxide

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About This Item

Linear Formula:
SiO2
CAS Number:
14808-60-7
Molecular Weight:
60.08
EC Number:
238-878-4
MDL number:
MFCD00011232
UNSPSC Code:
12352300
PubChem Substance ID:
329824458
NACRES:
SB.52

Assay

~99%

form

powder

particle size

0.5-10 μm (approx. 80% between 1-5 μm)

SMILES string

O=[Si]=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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Linkage

Historically called amorphous.

Preparation Note

A naturally occurring microcrystalline silica which has been finely ground.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H372

Precautionary Statements

P260 - P264 - P270 - P314 - P501

Hazard Classifications

STOT RE 1 Inhalation

Target Organs

Lungs

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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American journal of respiratory cell and molecular biology, 48(4), 448-455 (2012-12-22)
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Cell death & disease, 8(3), e2657-e2657 (2017-03-10)
Following inhalation into the lungs, silica particles are engulfed by alveolar macrophages, which triggers endogenous or exogenous apoptosis signaling pathways. As an inducer of apoptosis, the role of BBC3/PUMA (BCL2-binding component 3) in macrophages during silicosis remains unknown. Here, we
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