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46494

Supelco

Nifuroxazide

VETRANAL®, analytical standard

Synonym(s):

5-Nitro-2-furaldehyde p-hydroxybenzoylhydrazone

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About This Item

Empirical Formula (Hill Notation):
C12H9N3O5
CAS Number:
Molecular Weight:
275.22
Beilstein:
4264976
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

Oc1ccc(cc1)C(=O)N\N=C\c2ccc(o2)[N+]([O-])=O

InChI

1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+

InChI key

YCWSUKQGVSGXJO-NTUHNPAUSA-N

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General description

Nifuroxazide is an oral antibiotic, which may be used for the treatment of diarrhea.

Application

Nifuroxazide may be used as a reference standard in the determination of the analyte in plasma samples using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Philippe Quillardet et al.
Mutagenesis, 21(5), 305-311 (2006-08-10)
Nitrofurans are widely used in human medicine, as nitrofurantoin and nifuroxazide, still prescribed for long-term antimicrobial prophylaxis of urinary tract and gastrointestinal infection in humans respectively. Recent experiments in mammals, as well as reports mentioning toxic effects in humans associated
Akilimali Shindano et al.
Acta gastro-enterologica Belgica, 70(1), 32-33 (2007-07-11)
We report the case of a middle-aged woman who developed a typical picture of acute pancreatitis together with systemic features of immunoallergy after the intake of two capsules (200 mg) of nifuroxazide. Even if acute pancreatitis is a rare adverse
Mariane B Fernandes et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(3), 535-540 (2012-01-31)
It is important to determine the toxicity of compounds and co-solvents that are used in cell monolayer permeability studies to increase confidence in the results obtained from these in vitro experiments. This study was designed to evaluate the cytotoxicity of
B G Cipolla et al.
Amino acids, 33(2), 203-212 (2007-06-21)
Polyamine contents were assessed by mass spectrometry in 233 current foods and beverages. In order to reduce gut polyamine uptake, a polyamine reduced diet (PRD) and partial intermittent intestinal tract decontamination (PIITD) with neomycin or nifuroxazide was proposed as nutritional
Liang Yang et al.
Antimicrobial agents and chemotherapy, 53(6), 2432-2443 (2009-04-15)
Attenuation of Pseudomonas aeruginosa virulence by the use of small-molecule quorum-sensing inhibitors (referred to as the antipathogenic drug principle) is likely to play a role in future treatment strategies for chronic infections. In this study, structure-based virtual screening was used

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