16682
(R)-Pantoic acid sodium salt
≥95% (GC)
Synonym(s):
(2R)-2,4-Dihydroxy-3,3-dimethylbutanoic acid monosodium salt, (R)-2,4-Dihydroxy-3,3-dimethylbutyric acid sodium salt, Sodium (R)-pantoate, Sodium D-pantoate
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About This Item
Empirical Formula (Hill Notation):
C6H11NaO4
CAS Number:
Molecular Weight:
170.14
Beilstein:
6119584
UNSPSC Code:
12352106
NACRES:
NA.25
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Quality Level
Assay
≥95% (GC)
optical activity
[α]/D 8.0±1.0°, c = 1 in H2O
storage temp.
−20°C
InChI
1S/C6H12O4.Na/c1-6(2,3-7)4(8)5(9)10;/h4,7-8H,3H2,1-2H3,(H,9,10);/q;+1/p-1/t4-;/m0./s1
InChI key
XTIMSSMEPPKSQD-WCCKRBBISA-M
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Biochem/physiol Actions
(R)-Pantoic acid is an intermediate in the phosphopantothenate biosynthesis pathway for the de novo synthesis of R-pantothenate (vitamin B5) from valine in plants and microorganisms.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Although bacteria and eukaryotes share a pathway for coenzyme A (CoA) biosynthesis, we previously clarified that most archaea utilize a distinct pathway for the conversion of pantoate to 4'-phosphopantothenate. Whereas bacteria/eukaryotes use pantothenate synthetase and pantothenate kinase (PanK), the hyperthermophilic
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Ketopantoic acid (KPA) reductase catalyzes the stereospecific reduction of ketopantoic acid to D-pantoic acid. Based on the N-terminal amino acid sequence of KPA reductase from Stenotrophomonas maltophilia 845, the KPA reductase gene was cloned from S. maltophilia NBRC14161 and sequenced.
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Pantetheine and its corresponding disulfide pantethine play a key role in metabolism as building blocks of coenzyme A (CoA), an essential cofactor utilized in ~4% of primary metabolism and central to fatty acid, polyketide, and nonribosomal peptide synthases. Using a
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