Skip to Content
Merck
All Photos(1)

Documents

3867

Sigma-Aldrich

Hydrocortisone

Steroid hormone of the adrenal cortex with anti-inflammatory properties.

Synonym(s):

Hydrocortisone, Cortisol

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C21H30O5
CAS Number:
50-23-7
Molecular Weight:
362.46
MDL number:
MFCD00011654
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white to off-white

solubility

ethanol: 15 mg/mL

shipped in

ambient

storage temp.

10-30°C

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

JYGXADMDTFJGBT-VWUMJDOOSA-N

General description

Steroid hormone of the adrenal cortex with anti-inflammatory properties.
Steroid synthesized by the adrenal cortex. Important in the regulation of protein, nucleic acid, and lipid metabolism. Pharmacologically, hydrocortisone is used to suppress the inflammatory response.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Steroid hormone of the adrenal cortex with anti-inflammatory properties
Product does not compete with ATP.
Reversible: no

Warning

Toxicity: Carcinogenic / Teratogenic (D)

Preparation Note

Heating to 37°C may be required for complete solubilization.

Reconstitution

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 month at 4°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H360Df,H373

Hazard Classifications

Repr. 1A - STOT RE 2

Target Organs

Adrenal gland,Bone marrow

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

hEGF EGF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Sigma-Aldrich

E9644

hEGF

Sigma-Aldrich

Sigma-Aldrich

I9278

Insulin solution human

Simone Sandoval et al.
Frontiers in immunology, 14, 1193535-1193535 (2023-11-30)
Neuropilin-1 (Nrp1), a transmembrane protein expressed on CD4+ T cells, is mostly studied in the context of regulatory T cell (Treg) function. More recently, there is increasing evidence that Nrp1 is also highly expressed on activated effector T cells and
Hong-Yu Wu et al.
iScience, 27(6), 109850-109850 (2024-05-23)
Milk fat is an important indicator for evaluating the quality of cow's milk. In this study, we used bovine mammary epithelial cells (BMECs) to investigate the role and molecular mechanism of KLF4 in the regulation of milk fat synthesis. The
Xiaoxiang Hou et al.
Journal of neuroinflammation, 21(1), 148-148 (2024-06-06)
White matter injury (WMI) represents a significant etiological factor contributing to neurological impairment subsequent to Traumatic Brain Injury (TBI). CD36 receptors are recognized as pivotal participants in the pathogenesis of neurological disorders, including stroke and spinal cord injury. Furthermore, dynamic
Abhishek Mukherjee et al.
PLoS computational biology, 16(10), e1008300-e1008300 (2020-10-10)
Large nuclear deformations during migration through confined spaces have been associated with nuclear membrane rupture and DNA damage. However, the stresses associated with nuclear damage remain unclear. Here, using a quasi-static plane strain finite element model, we map evolution of
Lei Liu et al.
Journal of dairy science, 104(12), 12871-12880 (2021-09-07)
Susceptibility to mastitis is highest during the peripartal (transition) period and is often concomitant with other comorbidities such as ketosis. Although infection with pathogenic microorganisms and immune-dysfunction around calving clearly play key roles in mastitis development, other metabolic factors also
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service