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860556C

Avanti

18:1-12:0 Biotin DG

Avanti Research - A Croda Brand 860556C

Synonym(s):

1-oleoyl-2-[12-biotinyl(aminododecanoyl)]-sn-glycerol

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About This Item

Empirical Formula (Hill Notation):
C43H77N3O7S
CAS Number:
Molecular Weight:
780.15
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 1 mL (860556C-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860556C

concentration

1 mg/mL (860556C-1mg)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](CO)(OC(CCCCCCCCCCCNC(CCCC[C@]1([H])SC[C@@]2([H])[C@]1([H])NC(N2)=O)=O)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C43H77N3O7S/c1-2-3-4-5-6-7-8-9-10-11-12-14-17-20-23-30-40(49)52-34-36(33-47)53-41(50)31-24-21-18-15-13-16-19-22-27-32-44-39(48)29-26-25-28-38-42-37(35-54-38)45-43(51)46-42/h9-10,36-38,42,47H,2-8,11-35H2,1H3,(H,44,48)(H2,45,46,51)/b10-9-/t36-,37-,38-,42-/m0/s1

InChI key

DPGSXRFXXINSBQ-QYFPMEDBSA-N

General description

18:1-12:0 Biotin DG or 1-oleoyl-2-[12-biotinyl(aminododecanoyl)]-sn-glycerol is a triglyceride derivative wherein aminododecyl forms an amide bond with biotin to yield a biotinylated triglyceride.

Packaging

5 mL Amber Glass Screw Cap Vial (860556C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3


Certificates of Analysis (COA)

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Leslie A McCauliff et al.
eLife, 8 (2019-10-04)
Unesterified cholesterol accumulation in the late endosomal/lysosomal (LE/LY) compartment is the cellular hallmark of Niemann-Pick C (NPC) disease, caused by defects in the genes encoding NPC1 or NPC2. We previously reported the dramatic stimulation of NPC2 cholesterol transport rates to

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