S0381

Spermidine phosphate salt hexahydrate

• Synonym(s): Dispermidine triphosphate
• Linear Formula: [NH₂(CH₂)₃NH(CH₂)₄NH₂]₂ · 3H₃PO₄ · 6H₂O
• CAS Number: 23273-82-7
• Molecular Weight: 346.28
• MDL number: MFCD04966492
• UNSPSC Code: 12352100
• PubChem Substance ID: 57654594
• NACRES: NA.22

Properties

• storage temp.: −20°C
• SMILES string: O.O.O.O.O.O.OP(O)(O)=O.OP(O)(O)=O.OP(O)(O)=O.NCCCCNCCCN.NCCCCNCCCN
• InChI: 1S/2C7H19N3.3H3O4P.6H2O/c2*8-4-1-2-6-10-7-3-5-9;3*1-5(2,3)4;;;;;;/h2*10H,1-9H2;3*(H3,1,2,3,4);6*1H2
• InChI key: UYNKOICVVIGVMD-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA, may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

Caution

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves